Korean College of Laboratory Animal Medicine

KCLAM Role Delineation Document

The Role Delineation Document (RDD) contains the roles of KCLAM Diplomate and KCLAM members.

Overview: KCLAM RDD consists of six domains.

1. Domain 1 : Management of spontaneous and experimentally induced disease and condition
2. Domain 2 : Management of pain and distress
3. Domain 3 : Research
4. Domain 4 : Animal care
5. Domain 5 : Regulatory responsibilities
6. Domain 6 : Education

Domain: each domain contains task and knowledge for three categories

1. During the DVM program : No obligatory task but need knowledge for DVM licensed subject
2. At the time of certification : KCLAM diplomate performs most tasks and has most of the knowledge necessary to perform them.
3. Either on the job or in a continuing education setting after certification : Some tasks are performed, and knowledge is acquired through training.

Domain 1 : Management of spontaneous and experimentally induced disease and condition

During a DVM program
Task	None
Knowledges	K1 Diagnostic procedures Conduct a physical examination Clinical pathology Other diagnostic procedures K2 Surgical techniques associated with diagnostic and therapeutic surgeries (eg, autopsy or surgeries) K3 Immunobiology (eg, antibody-antigen reaction) K4 Nutrition with an emphasis on the effects of deficiency or toxicity K5 Anatomy with emphasis on features which have significance concerning clinical medicine or experimental medicine K6 Physiology with an emphasis on normative data and characteristics, metabolic differences or metabolism of induced disease, reproductive physiology, and clinically significant physiological features K7 Parasitology with emphasis on parasitic diseases that can become established in a colony and zoonotic parasitic diseases
At time of certification
Task	T1prevent spontaneous or unintended disease or condition T2control spontaneous or unintended disease or condition T3diagnose disease or condition as appropriate T4treat disease or condition as appropriate
Knowledges	K8 Microbiology with an emphasis on organisms of clinical significance; subclinical infections that cause physiologic, biochemical, and/or immunologic alterations; zoonotic disease organisms; organisms used experimentally to induce infection and unintended infections; and sampling and culture techniques for such organisms K9 Anatomic pathology including pathogenesis of significant naturally occurring and experimentally induced diseases; typical gross and histopathologic lesions; and pertinent anatomic pathology techniques K10 Pharmacology with emphasis on drugs used to treat spontaneous or induced disease and drugs used to induce disease K11 epidemiology including species-specific susceptibility to induced disease K12 preventive medicine K13 Diagnostic procedures species-specific behavioral assessment serologic, cytologic, and molecular diagnostic tests and proper sampling techniques K10 genetics with emphasis on control and treatment of naturally occurring and experimentally induced disease, predisposition to disease, and modes of inheritance

Domain 2 : Management of Pain and Distress

During a DVM program
Task	None
Knowledges	K1anatomy and physiology of pain and distress K2patient monitoring K3critical and post-procedural care techniques K4pharmacological interventions for pain and distress and their effects on physiology, including age and species differences for such interventions, and depth and duration of analgesia provided by such interventions K5Euthanasia K6causes of pain K7causes of distress K8humane endpoint criteria
At the time of certification
Task	T1recognize pain and/or distress T2minimize or eliminate pain and/or distress T3administration of anesthesia T4euthanatize (euthanize)
Knowledges	K9assessment of pain and distress K10effects of pain and distress on normative physiology and research studies K11nonpharmacological interventions for pain and distress and their effects on physiology, including age and species differences for such interventions

Domain 3 : Research

During a DVM program
Task	None
Knowledges	K1research methods and equipment K2principles of experimental design and statistics including the scientific method K3animal models including normative biology relevant to the research K4characterization of animal models K5genetics and nomenclature K6genetic modification/engineering technology including the application of molecular biology techniques K7bio methodology techniques K8gnotobiotics K9scientific writing K10Replacement, Reduction and Refinement techniques K11experimental surgical techniques and instrumentation
At the time of certification
Task	T1facilitate or provide research support T2advise and consult with investigators on matters related to their research T3design and conduct research
Knowledges	K12information resources K13Effective methods for communicating research-related concerns K14Aseptic requirements for performing surgery K15genomics, metabolomics, and proteomics
After certification
Task	T1collaborate with other scientists on research projects
Knowledges	K16the grant application, review and funding mechanisms

Domain 4 : Animal care

During a DVM program
Task	None
Knowledges	K1species-specific husbandry (eg, nutrition, housing, behavior) K2methods of sterilization, sanitation, and decontamination K3breeding colony management K4animal identification systems K5pest control K6environmental causes of physiological alterations in animals and their effects on research K7environmental monitoring K8watering and feeding K9pathogen-free barriers, maintenance of pathogen-free colonies via sentinel use and surveillance programs K10containment facilities
At the time of certification
Task	T1develop animal husbandry programs T2manage or provide indirect management/oversight of animal husbandry programs T3manage or provide indirect management/oversight of laboratory animal facilities
Knowledges	K11environmental enrichment, species-appropriate behavioral and psychosocial needs including creation and maintenance of appropriate social pairs or groups K12quality assurance techniques for animal care-related equipment and supplies K13animal procurement considerations
After certification
Task	T4design laboratory animal facilities, inspection
Knowledges	K14selection criteria for animal care-related equipment and supplies K15fiscal management as it relates to budgetary and financial issues associated with animal facility management K16human resource management as it relates to the operation of animal care and use programs K17disaster planning K18facility planning, design, and construction K19mechanical, electrical and plumbing systems K20waste management K21housing systems

Domain 5 : Regulatory Responsibilities

During a DVM program
Task	None
Knowledges	K1Laws, regulations, policies, and standards Welfare and Management of Animals Act Infectious Disease Control Law Domestic Animal Infectious Diseases Control Act K2role and function of the IACUC
At the time of certification
Task	T1perform direct or delegated Attending Veterinarian responsibilities T2advocate for humane care and use of animals T3provide advice to occupational health and safety programs T4provide advice on biological, chemical and radiation hazards in an animal research program T5serve as a member of an IACUC T6review protocols and provide advice to investigators and the IACUC
Knowledges	K3Laws, regulations, policies, and standards Good Laboratory Practices Pharmaceuticals and Medical Devices Act Narcotics and Psychotropics Control Act Conservation of Endangered Species of Wild Fauna and Flora Act Industrial Safety and Health Act Animal Protection Act (MAFRA, Korea Rep) Laboratory Animal Act (MFDS, Korea Rep) K4International laws, regulations, policies, and standards Guide for the Care and Use of Laboratory Animals (ILAR/NRC) AVMA Guidelines for the Euthanasia of Animals (AVMA) K5protocol review
After certification
Task	None
Knowledges	K6International laws, policies, and standards Animal Welfare Act, USDA regulations, Animal Care policies Health Research Extension Act, Public Health Service Policy on Humane Care and Use of Laboratory Animals, OLAW interpretive guidance Biosafety in Microbiological and Biomedical Laboratories Endangered Species Act/CITES Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (FASS) Live Animals Regulations (IATA - International Air Transportation Association) USDA and CDC animal importation regulations NIH Recombinant DNA Guidelines and Office of Biotechnology Occupational Health and Safety in the Care and Use of Research Animals (ILAR/NRC) Occupational Health and Safety in the Care and Use of Nonhuman Primates Other countries or regions (EU Directives) K7facility inspection and program review K8occupational health and safety K9role and function of the Institutional Biosafety Committee (IBC) K10role and function of AAALAC International K11responsible conduct of research

Domain 6 : Education

During a DVM program
Task	None
Knowledges	K1societal issues involving the use of animals : philosophy and ethics of animal use. history and value of animal research
At the time of certification
Task	T1train personnel in animal care and use T2maintain current knowledge and continued competence in laboratory animal medicine
Knowledges	K2educational resources K3certification programs (e.g., DKCLAM certification) K4societal issues involving the use of animals : organizations related to and/or supportive of laboratory animal medicine and animal research (e.g., KALAS, KSLAV, ILAR) organizations opposed to animal research including their philosophy and opposition strategies
After certification
Task	T3provide education in academic and/or laboratory animal residency programs T4outside of formal training programs, mentor those interested in or involved in laboratory animal medicine T5provide community outreach on animal care and use
Knowledges	None

Species Categories (KCLAM specific)

The suggested species were classified as primary, and secondary. Below is the list by category.

Category	Species
Primary	P1Mouse (Mus musculus) P2Rat (Rattus norvegicus) P3Rabbit (Oryctolagus cuniculus) P4Dog (Canis familiaris) P5Pig (Sus scrofa) P6Macaques (Macaca spp)
Secondary	S1Guinea pig (Cavia porcellus) S2Syrian hamster (Mesocricetus auratus) S3Gerbil (Meriones spp.) S4Other rodents S5Cat (Felis domestica) S6Ferret (Mustela putorius furo) S7Sheep (Ovis aries) S8Goat (Capra hircus) S9Squirrel monkey (Saimiri sciureus) S10Marmoset/tamarins (Callitrichidae) S11Another nonhuman primate S12Chicken (Gallus domestica) S14Other birds S12Zebrafish (Danio rerio) S15Other fish S16African clawed frog (Xenopus laevis and Xenopus tropicalis) S20Invertebrates including drosophila and nematode